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Moore turned over a 1963 memorandum by the companys general counsel stating that Brown & Williamson was selling nicotine, an addictive drug.[16] Because the documents contradicted testimony given the prior month by Brown & Williamson CEO Thomas Sandefur, the subcommittee scheduled a hearing to recall him

[87] Presently, approximately 8 million individuals succumb to tobacco-related diseases annually, resulting in a significant economic burden of $1.4 trillion on the global scale each year

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They found that over 6,000 CpGs were differentially methylated in offspring exposed to maternal smoking including several genes that were critical in development [49]